I was thinking the other day and came up with a few ideas about hypertrophy training. Basically I think I found a way to express it in just one short sentence: hypertrophy training is the middle ground training. At one end of the spectrum, you have extreme strength training: very few reps, lots of rest between sets, very heavy weights. You're training your CNS. At the other end, metabolic conditioning: lots of reps, little rest between sets, low weights. You fatigue your muscles to the extreme. Neither of those ends is good for significant muscle hypertrophy.
From all the articles I've read, all the books, all the internet forums, etc it appears to me that hypertrophy training falls right in between the two ends of the spectrum: you use medium reps, medium rest, medium weights. You're not training exclusively for strength, but you're not really training for endurance either. Or better yet, you train both. You cannot sacrifice one too much for the other.
If you use too few reps you won't be fatiguing the muscles enough, not breaking down enough muscle fibers. On the other hand, too many reps and the resistance is not strong enough: there will be no stimulus for growth.
Too much rest? Not optimal for growth hormone release. Too little? the weights will have to go down and the resistance won't be strong enough.
So all of the time, you have to strike a balance. Not too much rest between sets, like a powerlifter, and not too little (like someone training for endurance). Not too many reps, not too few...
The rest is just fine tuning and varies from individual to individual. Basically you just have to shoot for the middle ground.
Am I way off or is there some truth to this? I wanted to share it with you guys because it almost feels too simple to be true. Of course I assume everything else is equal (right exercise selection, good nutrition and rest, etc).